\documentclass[10pt]{article}

\usepackage{fullpage}
\usepackage{setspace}
\usepackage{parskip}
\usepackage{titlesec}
\usepackage[section]{placeins}
\usepackage{xcolor}
\usepackage{breakcites}
\usepackage{lineno}
\usepackage{hyphenat}





\PassOptionsToPackage{hyphens}{url}
\usepackage[colorlinks = true,
            linkcolor = blue,
            urlcolor  = blue,
            citecolor = blue,
            anchorcolor = blue]{hyperref}
\usepackage{etoolbox}
\makeatletter
\patchcmd\@combinedblfloats{\box\@outputbox}{\unvbox\@outputbox}{}{%
  \errmessage{\noexpand\@combinedblfloats could not be patched}%
}%
\makeatother


\usepackage{natbib}




\renewenvironment{abstract}
  {{\bfseries\noindent{\abstractname}\par\nobreak}\footnotesize}
  {\bigskip}

\titlespacing{\section}{0pt}{*3}{*1}
\titlespacing{\subsection}{0pt}{*2}{*0.5}
\titlespacing{\subsubsection}{0pt}{*1.5}{0pt}


\usepackage{authblk}


\usepackage{graphicx}
\usepackage[space]{grffile}
\usepackage{latexsym}
\usepackage{textcomp}
\usepackage{longtable}
\usepackage{tabulary}
\usepackage{booktabs,array,multirow}
\usepackage{amsfonts,amsmath,amssymb}
\providecommand\citet{\cite}
\providecommand\citep{\cite}
\providecommand\citealt{\cite}
% You can conditionalize code for latexml or normal latex using this.
\newif\iflatexml\latexmlfalse
\providecommand{\tightlist}{\setlength{\itemsep}{0pt}\setlength{\parskip}{0pt}}%

\AtBeginDocument{\DeclareGraphicsExtensions{.pdf,.PDF,.eps,.EPS,.png,.PNG,.tif,.TIF,.jpg,.JPG,.jpeg,.JPEG}}

\usepackage[utf8]{inputenc}
\usepackage[english]{babel}



\usepackage{float}








\begin{document}

\title{Improving Stability and Accuracy of Cell Viability Evaluation by Fusion
of Impedance Spectroscopy Information}



\author[1]{Yecheng Zhang}%
\author[1]{Mingji Wei}%
\author[1]{Rongbiao Zhang}%
\author[1]{Fei Zhang}%
\affil[1]{Jiangsu University}%


\vspace{-1em}



  
  \date{June 14, 2024}


\begingroup
\let\center\flushleft
\let\endcenter\endflushleft
\maketitle
\endgroup





\selectlanguage{english}
\begin{abstract}
The increasing attention to precision medicine is widely paid in order
to greatly improve the cure rate of cancer. Improving the stability and
accuracy of cell viability evaluation is the key of precision medicine,
for excess dosage of anti-cancer drugs not only kills the cancer cells,
but also does harm to normal cells. Electrochemical impedance sensing
(EIS) method is widely accepted as a label-free, non-invasive approach
for real-time, online monitoring of cell viability. Due to the large
effects of many influencing factors, the existing EIS methods that
utilized single-frequency impedances show poor stability and low
accuracy of cell viability evaluation. In this paper, we proposed a
multi-physical information fusion method based on least squares support
vector machine (LS-SVM) for improving the stability and accuracy of cell
viability evaluation. The results show that the mean relative error of
single-frequency method is about 0.08, while that of fusion method is
about 0.04. It means that the prediction results of fusion method are
more accurate than that of the single-frequency method. Moreover, the
maximum relative error of single-frequency method is up to 0.5 due to
the influencing of cell micromotion, while that of fusion method is
below 0.07, showing that the fusion method is more stable than
single-frequency method.%
\end{abstract}%



\sloppy




\selectlanguage{english}
\FloatBarrier
\end{document}

