Funding:
This study was supported by the National Health and Medical Research Council (NHMRC) of Australia (research grants 299901 and 1021275); the University of Melbourne, the Clifford Craig Medical Research Trust of Tasmania; the Victorian, Queensland and Tasmanian Asthma Foundations; Royal Hobart Hospital; Helen MacPherson Smith Trust; GlaxoSmithKline; and John L Hopper. DL acknowledges the contribution of the Melbourne Research Scholarship (Fee offset) and Becas Carlos Antonio Lopez scholarship to undertake this study which relates to his doctoral candidature at the University of Melbourne. The funding agencies had no direct role in the conduct of the study; the collection, management, statistical analysis, and interpretation of the data; or the preparation or approval of the manuscript.