Gene family dynamics in the genome
Significant expansion and contraction of gene families may denote
environmental adaptation of the species. Based on both divergence time
estimation and OrthoMCL gene family clustering, CAFE was used to detect
dynamics of gene families residing in the genome. The analysis detected
431 expanded gene families, as well as 491 contracted gene families, in
the T. dalaica genome. The top three enriched pathways for
expanded family genes were “Gap junction”, “Relaxin signaling
pathway”, and “Bile secretion”, while for contracted family genes,
the top three were “Estrogen signaling pathway”, “Dopaminergic
synapse”, and “Parathyroid hormone synthesis, secretion, and action”
(Table S6).