Conflict of interest:
Dr Gianni Mistrello and Enrico Compalati are employees of Lofarma.
Prof. Mario Di Gioacchino reports grants and personal fees from GSK,
grants from Novartis, grants, personal fees and non-financial support
from Lofarma, personal fees from Menarini, grants from SanofiGenzyme
outside the submitted work.
Prof. Claudia Petrarca reports grants from Lofarma
The other authors have no conflict to declare