Statistical Analysis
Due to the exploratory nature of this small cohort pilot study, there was no calculation in sample size. It was not possible to estimate the real incidence of arrhythmias with the use of local dental anesthetics in patients with CCh and ICD, since literature is limited by the absence of studies in this population.
All variables were analyzed quantitatively, including the observation of the minimum and maximum measured parameter values and the calculation of means, SDs, and medians. All qualitative variables were calculated with absolute and relative frequencies. For comparison between 2 groups in relation to the means, we used the paired Student’s t test. The Wilcoxon signed-rank test was used when the normality assumption was rejected.
Statistical analysis was performed using the SPSS (Statistical Package for the Social Sciences), version 20.0 (SPSS, Inc, Chicago, IL). All tests were two tailed and the level of significance was set at 5%.