Study selection and characteristics
After application of inclusion and exclusion criteria, a total of 46
studies5-50 consisting
of 6313 patients included in this meta-analysis (Figure 1). The
patients’ mean age was 57.5 (95% CI 55.1 to 55.9). The frequency of
males and females was 73% (95% CI 70 to 76) and 27% (95% CI 23.8 to
30), respectively, reporting by forty-five studies. The cumulative
frequency of acute dissection, chronic dissection, and aneurysm in
studies reporting aortic pathologies was 72.5% (95% CI 60.1 to 84.2),
36.2% (95% CI 24 to 48.4), and 48.2% (95% CI 34.1 to 62.3),
respectively. The prevalence of prior cerebrovascular accidents and
chronic kidney disease was 7.7% (95% CI 5.3 to 10.1) and 12.5 % (95%
CI 5.4 to 19.7), respectively. The FET hybrid stent graft is mostly used
in China (17 studies including 3314 patients), Japan (8 studies
including 526 patients), and Germany (8 studies including 425 patients).
Other baseline characteristics are summarized in Table 1 and
Supplementary Table 2.
A total of 258 and 1000 patients underwent only elective or only
emergent/urgent surgeries in 7 and 10 studies, respectively. Concomitant
Bentall and David surgeries were performed in 22.2% (95% CI 15.6 to
28.8) and 10.7% (95% CI 5.6 to 15.7) of patients reporting by 27 and
21 studies, respectively. The mostly used FET stents included
Cronus® (MicroPort Medical, Shanghai, China),
E-vita® (JOTEC™ GmbH, Hechingen, Germany), and
Thoraflex Hybrid® (Vascutek, Inchinnan, UK) in 3194,
1612, 1011 patients, respectively. Other surgical features were
summarized in Table 2.