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\begin{document}

\title{Evaluation of narrow band imaging for diagnosis of unilateral nasal
lesions}



\author[1]{Dachuan Fan}%
\author[1]{Jinxiao Hou}%
\author[2]{Tianhong Zhang}%
\author[2]{Yijing Ye}%
\affil[1]{the Second Affiliated Hospital of Anhui Medical University}%
\affil[2]{First Affiliated Hospital of Harbin Medical University}%


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  \date{June 16, 2024}


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\begin{abstract}
Objectives: To investigate the effect of NBI examination on the
differentiating between benign and malignant neoplasms involving nasal
cavity. Design, Setting, Participants: A retrospective case series from
January 2018 to December 2019 were performed at a single center. A total
of 188 consecutive patients who were first diagnosed with lesions in
unilateral nasal cavity underwent complete examination with white light
endoscopy (WLE) and NBI endoscopy, respectively. Biopsy was harvested
from the target lesion and sent to the pathologist for definite
diagnosis. Participants with a history of congenital malformation,
trauma and surgery in nasal cavity were excluded from the study. Main
outcome measures: Endoscopic diagnosis was assessed using sensitivity,
specificity, accuracy and positive and negative predictive values (PPV
and NPV, respectively). Results: In identifying benign and malignant
lesions of nasal cavity, NBI had a significant higher sensitivity
(92.7\% vs 70.7\%, P = 0.020) and NPV (98\% vs 92.3\%, P = 0.032) than
WLE, but there were no significant differences between NBI and WLE in
specificity (98.6\% vs 97.3\%, P = 0.684), accuracy (97.3\% vs 91.5\%, P
= 0.416) and PPV (95\% vs 87.9\%, P = 0.400). Conclusion: The emerging
technique of NBI can improve the diagnostic accuracy of distinguishing
benign and malignant lesions in nasal cavity, and remains a promising
and helpful adjunct to the traditional endoscopy techniques.%
\end{abstract}%



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