Fig. 3. Immunohistochemically, majority of the lymphocytes expressed CD3, CD5, & CD4, (A, B, C); a few CD8+ cells, low Ki67 (10%), & CD30 negativity (D,E,F) (x40).
Refrences :
1. Willemze R, Jaffe ES, Burg G, Cerroni L, Berti E, Swerdlow SH, et al. WHO-EORTC classification for cutaneous lymphomas. Blood. 2005;105(10):3768-85.
2. Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood, The Journal of the American Society of Hematology. 2016;127(20):2375-90.
3. Beltraminelli H, Leinweber B, Kerl H, Cerroni L. Primary cutaneous CD4+ small-/medium-sized pleomorphic T-cell lymphoma: a cutaneous nodular proliferation of pleomorphic T lymphocytes of undetermined significance? A study of 136 cases. The American Journal of dermatopathology. 2009;31(4):317-22.
4. Gru AA, Wick MR, Eid M. Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder-clinical and histopathologic features, differential diagnosis, and treatment. Semin Cutan Med Surg. 2018;37(1):39-48.
5. Baum CL, Link BK, Neppalli VT, Swick BL, Liu V. Reappraisal of the provisional entity primary cutaneous CD4+ small/medium pleomorphic T-cell lymphoma: a series of 10 adult and pediatric patients and review of the literature. Journal of the American Academy of Dermatology. 2011;65(4):739-48.
6. Kim J, Jeong M, Jun D, Lee M, Shin D, Kim W, et al. Primary cutaneous CD4+ small/medium T-cell lymphoma: a case report. Archives of Craniofacial Surgery. 2021;22(4):199.
7. Salah E. Primary cutaneous CD4+ small/medium pleomorphic T-cell lymphoproliferative disorder: Where do we stand? A systematic review. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 2019;17(2):123-36.
8. Escanilla C, Guavita Falla PM, Cevallos C, Ávalos Jobet N, Bobadilla Bruneau F. Primary cutaneous CD4-positive small/medium T-cell lymphoproliferative disorder: The first-reported Latin-American case with response to doxycycline. Clinical case reports. 2019;7(12):2405-9.
9. Li D, Guo B, Li D, Chang C, Lu Q. Primary cutaneous CD4+ small-to-medium-sized pleomorphic T-cell lymphoma: a rare case report of infant. Journal of clinical pathology. 2015;68(10):855-8.
10. Grogg KL, Jung S, Erickson LA, McClure RF, Dogan A. Primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma: a clonal T-cell lymphoproliferative disorder with indolent behavior. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2008;21(6):708-15.
11. Messeguer F, Gimeno E, Agusti-Mejias A, San Juan J. [Primary cutaneous CD4+ small- to medium-sized pleomorphic T-cell lymphoma: report of a case with spontaneous resolution]. Actas dermo-sifiliograficas. 2011;102(8):636-8.
12. González Fernández D, Valdés Pineda F, Gómez Díez S, Vivanco Allende B. Primary Cutaneous CD4+ Small/Medium-Sized T-Cell Lymphoma With Spontaneous Regression After Biopsy. Actas dermo-sifiliograficas. 2015;106(9):767-8.
13. Friedmann D, Wechsler J, Delfau MH, Estève E, Farcet JP, de Muret A, et al. Primary cutaneous pleomorphic small T-cell lymphoma. A review of 11 cases. The French Study Group on Cutaneous Lymphomas. Archives of dermatology. 1995;131(9):1009-15.