Material and Methods
85 patients aged 1 month to 18 years who applied to Dicle University
Faculty of Medicine between 15.03.2020 and 20.05.2020 were included in
the study. 40 patients who were diagnosed to have COVID-19 and
hospitalized with the real-time reverse transcription polymerase chain
reaction (RT-PCR) method were included. The control group was composed
of 45 healthy patients who had previously applied to Pediatric
Endocrinology or Pediatric outpatient clinics and whose vitamin D level
was checked. Those with chronic diseases and an additional disease, and
those younger than 1 month and older than 18 were excluded from the
study. The data of the cases included in the study were obtained from
retrospective file records. The age of admission, clinical and
laboratory data, and 25-hydroxycholecalciferol (25-OHD) and parathormone
(PTH) levels were recorded. 25-hydroxycholecalciferaol level was
examined in Shimatzu device by high performance liquid chromatography
method. PTH level was examined by electro chemiluminescence method in
Siemens Advia Centaur device. Those with 25-OHD level <12ng/ml
were considered as vitamin D Deficiency, those between 12-20 ng/ml were
considered as Insufficiency of vitamin D and those with >20
ng/ml were considered Sufficiency (12). Patients diagnosed with COVID-19
were divided into 2 groups. Those with vitamin D levels which are below
20 ng/ml were determined as Group 1 and those with ≥20 ng/ml as Group 2,
and clinical and laboratory variables between the 2 groups were
compared.
The study was conducted based on the rules of Declaration of Helsinki
and approved by the Institutional Ethics Committee of Dicle University,
Faculty of Medicine.