Material and Methods
85 patients aged 1 month to 18 years who applied to Dicle University Faculty of Medicine between 15.03.2020 and 20.05.2020 were included in the study. 40 patients who were diagnosed to have COVID-19 and hospitalized with the real-time reverse transcription polymerase chain reaction (RT-PCR) method were included. The control group was composed of 45 healthy patients who had previously applied to Pediatric Endocrinology or Pediatric outpatient clinics and whose vitamin D level was checked. Those with chronic diseases and an additional disease, and those younger than 1 month and older than 18 were excluded from the study. The data of the cases included in the study were obtained from retrospective file records. The age of admission, clinical and laboratory data, and 25-hydroxycholecalciferol (25-OHD) and parathormone (PTH) levels were recorded. 25-hydroxycholecalciferaol level was examined in Shimatzu device by high performance liquid chromatography method. PTH level was examined by electro chemiluminescence method in Siemens Advia Centaur device. Those with 25-OHD level <12ng/ml were considered as vitamin D Deficiency, those between 12-20 ng/ml were considered as Insufficiency of vitamin D and those with >20 ng/ml were considered Sufficiency (12). Patients diagnosed with COVID-19 were divided into 2 groups. Those with vitamin D levels which are below 20 ng/ml were determined as Group 1 and those with ≥20 ng/ml as Group 2, and clinical and laboratory variables between the 2 groups were compared.
The study was conducted based on the rules of Declaration of Helsinki and approved by the Institutional Ethics Committee of Dicle University, Faculty of Medicine.