ADGRG2(GPR64) |
Adhesion |
efferent ductules;
proximal epididymis
(non-ciliated cells; principal cells)
|
fluid reabsorption |
Gs; Gq; β-arrestin-1 |
Davies
et al., 2004;
Gottwald et al., 2006;
Zhang et
al., 2018
|
AGTR2 |
Rhodopsin |
basal cells |
proton secretion |
unknown |
Shum et
al., 2008 |
LGR4 (GPR48) |
Rhodopsin |
epithelial cells in the reproductive organs |
epithelial-mesenchymal interactions |
Gs |
Mendive et
al., 2006;
Gao et al., 2006;
Li et al.,
2010
|
GPER (GPR30) |
Rhodopsin |
testis; spermatozoa; prostate; efferent
ductules; epididymis |
formation of blood-epididymal barrier and
regulation of osmotic pressure |
Gs; β-arrestin-2 |
Katleba et al., 2015;
Cao et al.,
2017
|
Adenosine receptor |
Rhodopsin |
epididymis |
contractility of the
epididymis |
Gs; Gi; β-arrestin |
Geldenhuys et al.,
2017;
Haynes et al., 1998b
|