Abstract

Although hepatoblastoma constitutes most of hapetic tumours in chidren, other types of tumors are often observed in older patients. We report a case of a 10-year-old Japanese boy with a transitional hepatic tumour consisting of both hepatoblastoma and hepatocellular carcinoma. After surgery and chemotherapy with cisplatin and pirarubicin, the tumour regressed, however, new tumours in the liver evolved with element of hepatocellular carcinoma. He died as a result of hepatic failure afte lenvatinib and drug-eluting transcatheter arterial chemoembolisation 18 months after diagnosis. Examinations of a panel of genomic alterations did not identify any therapeutic targets.