AUTHOR CONTRIBUTIONS
H.Z., L.Z., L.S. and H.Y. designed the study; Q.W., J.Z., and S.L. contributed new reagents or analytical tools; H.Z. conducted the laboratory work, analyzed data and took the lead in writing the manuscript; L.S. and H.Y. supervised the findings of this work. All authors provided critical feedback and helped to conduct the research, and approved the final manuscript.