What this study adds
- Human recombinant epidermal growth factor eyedrops were safe and
well-tolerated in healthy subjects.
- This study informed serum and tear pharmacokinetics after single and
multiple administration of human recombinant epidermal growth factor
eyedrops.
- This study provided information for further clinical study for corneal
injury treatment.
Keywords: dry eye disease, epidermal growth factor,
first-in-human study, pharmacokinetics