Demographics
Thirty-six healthy Korean male subjects were enrolled. Their mean age, height, weight, and body mass index were (mean ± standard deviation) 32.6 ± 6.1 years, 173.5 ± 5.8 cm, 68.5 ± 7.2 kg, and 22.7 ± 1.9 kg/m2, respectively. The demographic characteristics between sequences showed no statistical difference.
One subject withdrew consent before the first dosing and another withdrew during the treatment period. Therefore, 35 subjects were included in the safety assessment, and 34 were included in the PK and PD analyses.