Introduction:
Cystic Fibrosis (CF) is a genetic disease with progressive lung disease,
malnutrition, liver disease and CF-related diabetes (1). Viral
infections are a major factor causing pulmonary exacerbations in CF (2).
COVID-19 has caused a worldwide pandemic with high death rates. As
science suggests, patients with CF would be severely affected with a
high rate of morbidity, hospitalization and mortality. In a recent study
published by Cosgriff et al. (3) people with CF who were 15 years and
older, infected with COVID-19 appear to have better outcomes than
initially anticipated. We report the only two cases of CF in literature
less than 15 years of age with better than expected outcomes post
COVID-19 infection and discuss the possible effects of hypertonic Saline
as a plausible explanation.