Viral infections in childhood:
In children suffering from acute upper respiratory airway viral
infections, the incidence of exanthems after therapy with antibiotics
(mostly β-lactams) is high [35]. This phenomenon can be observed
following infections with a wide range of different viruses such as
picornavirus, coronaviruses, hMPV, influenza A-B, parainfluenza, and
RSV. These observed exanthems are mostly mild and transitory, but they
can have lasting consequences. For example, infected children can be
labeled as drug (“penicillin”)-allergic, but later no sensitization to
drugs is observed in skin tests and the eliciting drug is again well
tolerated [36].