Associations between Mortality and Extended Risk Criteria
We compared the outcomes of the recipients receiving ECD hearts to those
who received traditional-criteria donor hearts. We noted similar
long-term mortality between the recipients of donor hearts with LVEF
<60% compared to those with LVEF >60% (15.3%
vs 14.8%, p=0.52), those with >50 offers compared to ≤ 50
offers (15.1% vs 16.7%, p=0.32), HCV, HBV, and HIV positive versus
negative donors (15.2% vs 13.2%, p=0.18), and donors >500
compared to ≤500 miles from the transplant center (15.1% vs 16.0%,
p=0.51) (Supplemental Table 2 ). However, when compared to
recipients of donors ≤40 years, recipients of donor hearts
>40 years of age had higher rates of overall post-OHT
mortality (14.1% vs 18.4%, p<0.001).