Respiratory failure is a common cause of death. It is proven that Extracorporeal Membrane Oxygenation (ECMO) cannulation is successful in bridging patients to lung transplantation. Here we report on a 51-year-old patient with COPD who was bridged successfully to lung transplantation using venous-venous ECMO with a Protek Duo RD™ dual lumen cannula; which contributed to our success in bridging to transplant without the need for anticoagulation. Here we confirm that the clinical application use of the cannula without IV Heparin use is safe and feasible.