Platelet imaging
Platelets express several platelet-typical receptors on their surface. For molecular imaging, those receptors are of particular interest, which can be used to differentiate between resting and activated platelets. Thereby, selective targeting of activated platelets present in thrombi as compared to non-activated platelets in the circulation can be achieved. The two most attractive biomarkers for platelet activation used in molecular imaging are P-selectin and Glycoprotein (GP) IIb/IIIa.