Abstract

Bullfrog is one of the most important economic aquatic animals in China. It is widely cultured in southern China, and is a key breed recommended by China's poverty alleviation industry. In recent years, a fatal bacterial disease often occurs in cultured bullfrogs. The clinical manifestations of diseased bullfrog were severe intestinal inflammation and even anal prolapse. A bacterial pathogen was isolated from the diseased bullfrog intestine. The bacterium was identified as Vibrio cholerae by morphological, biochemical and 16S rRNA phylogenetic analysis. In this study, V. cholerae was isolated and identified from the diseased bullfrog for the first time, which provided the basis for the diagnosis and control of the disease. At the same time, it is also reminded that V. cholerae from bullfrog may be transmitted to human through bullfrog food and aquaculture water, which is a serious threat to human beings. The whole society should pay attention to it and formulate reasonable measures to avoid disasters.