QoL and mental health across different causes of anaphylaxis
There were no significant differences across the different causes of
anaphylaxis for reported stress or anxiety but there were significant
differences for depression across food, venom, medication or spontaneous
causes of anaphylaxis, F(3,134)=3.04, p<0.05. Post hoc tests
showed that those with anaphylaxis to medication reported significantly
greater depression than those reacting to bee or wasp venom.
There were significant differences across different causes for general
physical QoL as measured by the WHOQoL BREF, F (3,128)4.40,
p<0.01, but not for social, psychological or environmental
QoL. Post hoc tests showed that those with anaphylaxis to medication
reported significantly worse physical QoL than those reporting
anaphylaxis to venom (p<0.01).
For anaphylaxis specific overall QoL, there were significant differences
across food, venom, medication or spontaneous causes of anaphylaxis,
F(3,124)=6.50, p<0.001. Post hoc tests showed that those with
anaphylaxis to food had significantly poorer QoL than those reacting to
bee or wasp venom (p<0.02) or medication (p<0.05).
Those with spontaneous anaphylaxis reported significantly poorer QoL
than those with anaphylaxis to venom (p<0.01) or medication
(p<0.05).
For the sub-domains of the A-QoL-Adults scale, there were significant
differences across the different causes for Limitations on Life,
F(3,129)=7.34, p<0.001, Social QoL, F(3,130)=3.83,
p<0.01 and Emotional QoL, F(3,131)=4.49, p<0.01.
Post hoc tests showed that those with spontaneous anaphylaxis reported
poorer social QoL (p<0.05) and emotional QoL (p=0.01) than
those reacting to venom. Those reacting to food reported poorer
emotional QoL (p<0.01) than those reacting to venom and
greater limitations on life compared to those reacting to venom
(p<0. 05) or medication (p<0.001). Finally, those
with spontaneous anaphylaxis reported greater limitations on life than
those reacting to medication as a cause (p<0.05) (Table 4).