Statistical analysis
Data analyses were conducted using SPSS version 26. Differences in mean
scores from the study sample and published norm mean scores for the
WHOQoL BREF21, the PSS23 and the
HADS24 were analysed using one-sample t-tests.
Differences across categorical variables and across different
anaphylaxis trigger groups were analysed using t-tests and one-way
ANOVAs. When analysing across different trigger groups, participants
with anaphylaxis to more than one cause (n=2) were excluded to ensure
they were not counted more than once in the analysis. Relationships
between QoL, anxiety, depression, stress and continuous demographic and
clinical variables were analysed using Pearson’s correlations. Variables
significantly associated with anaphylaxis related QoL (as measured by
the A-QoL-Adults) were entered into a regression model to explore
significant predictors of QoL in adults. All tests were two-tailed and
alpha was set at 0.05. Sensitivity analysis showed that the study was
able to detect medium effect sizes with 80% power, with alpha set at
0.05.