Predictors of quality of life for adults with anaphylaxis
A hierarchical multiple regression model was run to explore predictors of anaphylaxis specific QoL. Predictors that significantly related to total QoL as measured by the A-QoL-Adult were entered into the model. Demographic and clinical variables were entered in the first step to explore the unique contribution of these variables and to then control for them; mental health variables were entered in the second step. The model for the first step was significant (F(4,94) = 6.54, p<0.001) and explained 19.1% of the variance in anaphylaxis specific QoL. A greater number of anaphylactic reactions experienced and being female were significant predictors of poorer anaphylaxis specific QoL. The model for the second step was also significant (F(8,94) = 18.55, p<0.001) and explained a further 40.9% of the variance, with 60% explained overall. In this model, age became significant, but gender was no longer significant. A greater number of anaphylactic reactions experienced and greater anxiety also significantly predicted poorer anaphylaxis specific QoL, with anxiety the strongest predictor (Table 5).