Characteristics N=32 patients
Mean age (SD) 51.8 ± 17.7
Body mass index 25.1 ± 4.7
Gender (N, %)
Male 10 (31.3)
Female 22 (68.7)
Gastrointestinal endoscopy N=21
Normal 2 (9.5)
Hiatal hernia 7 (33.3)
LES insufficiency 13 (61.9)
Esophagitis 11 (52.4)
Gastritis 10 (47.6)
Helicobacter Pylori infection 1 (4.8)
Types of LPR at the HEMII-pH
Acid LPR 15
Weakly acid LPR 10
Nonacid LPR 7
HEMII-pH feature (m ± SD)
Pharyngeal acid reflux episodes 34.8 ± 36.1
Pharyngeal nonacid reflux episodes 24.4 ± 18.3
Pharyngeal reflux episodes upright 22.1 ± 15.8
Pharyngeal reflux episodes supine 3.7 ± 5.3
Pharyngeal reflux episodes (total) 57.3 ± 44.2
GERD 17 (51.5)
Percentage of time with distal pH<4 6.9 ± 14.5
DeMeester score 20.4 ± 41.7
Responder rates N (%)
No response (chronic course) 7 (21.9)
Mild response 2 (6.2)
Moderate response 7 (21.9)
High response 12 (37.5)
Complete responses 4 (12.5)