Patients
Data from patients who underwent allogeneic PBSCT between January 2016
and December 2018 in Shanghai Children’s Medical Center and their paired
donors were reviewed retrospectively. Informed consent was obtained from
each patient or their family, following the principles of the
Declaration of Helsinki. Inclusion criteria included age under 18 years,
sustained remission of the underlying disease after PBSCT, a follow-up
period of more than 12 months, a complete set of clinical and medical
records, and no medical history of HBV infection. Exclusion criteria
included the failure to achieve remission or death during the study
period, HBV infection prior to transplantation and missing complete
records regarding HBsAb. Basic information about the patients, paired
donors and transplant-related complications was extracted
by retrospective review of the electronic medical records.