Lactobacillus and Nrf2
In mice, several strains of Lactobacillus were found to regulate Nrf2 in models of ageing 49, cardioprotective effects50, and non-alcoholic fatty acid liver disease51. Lactobacillus plantarum  CQPC11 - isolated from Sichuan pickled cabbages - antagonizes oxidation and ageing in mice52. Lactobacillus protects against ulcerative colitis by modulation of the gut microbiota and Nrf2/Ho-1 pathway53. The sugary kefir strain, Lactobacillus maliAPS1, \soutameliorated ameliorates? hepatic steatosis by regulation of Nrf2 and the gut microbiota in rats 54. In vitro studies have also found an effect of Lactobacilli mediated by Nrf2 55-57. Interestingly, the synbiotic combination of prebiotic grape pomace extract and probioticLactobacillus sp. \soutreduced reduces? intestinal inflammatory markers.58