AbstractAmiodarone, a widely utilized and effective class III antiarrhythmic agent, carries a significant risk of severe organ toxicities, notably including the pulmonary system. This report details a case of an 82-year-old female who developed amiodarone-induced pulmonary toxicity (APT) following two years of standard 200mg daily maintenance therapy for atrial fibrillation. The patient presented with progressive dyspnea, non-productive cough, and new-onset oxygen dependency. Diagnostic evaluation, including chest computed tomography revealing diffuse interstitial opacities, alongside the systematic exclusion of other etiologies, confirmed the diagnosis. Prompt discontinuation of amiodarone and initiation of corticosteroid therapy resulted in clinical stabilization. This case underscores the insidious nature of amiodarone-induced adverse effects, particularly in the elderly population, and reinforces the critical necessity for a high index of clinical suspicion and vigilant, proactive monitoring strategies to facilitate early detection and appropriate management of this potentially life-threatening iatrogenic complication, even with standard therapeutic dosages.

Calcification beyond basal ganglia is rare in postoperative permanent hypoparathyroidism. We report extensive bilateral intracranial calcifications involving basal ganglia, thalamus, cerebellum, and cerebral cortex in a 56-year-old lady who presented with carpopedal spasm, seizure, and severe hypocalcemia after 20 years of near-total thyroidectomy.

We report the case of a 73-year-old man who was presumed to have iron deficiency anemia and was treated with iron supplements since adolescence. His workup revealed β-thalassemia minor and H63D homozygous hereditary hemochromatosis complicated with liver cirrhosis and hepatocellular carcinoma.