Abstract
Introduction: It is not unusual for temporary transvenous cardiac pacing
(TVCP) leads to penetrate and occasionally perforate the right
ventricular wall, which generally is asymptomatic. The definition of
myocardial injury is evidence of elevated cardiac troponin (cTn) values
above the 99th percentile upper reference limit (URL). Myocardial injury
is associated with an adverse prognosis. The present study was designed
to evaluating myocardial injury complicated by TVCP. Methods:
Retrospective study from August 2018 to March 2020, 33 consecutive
patients undergo elective TVCP support for non-cardiac procedures, 22 of
them had cardiac biomarkers assays before and after TVCP. These 22
eligible patients had a median age of 66 (50-83) years, 6 (27.3%) were
women, and all baseline cTn <1 URL. Compare cardiac biomarkers
before and after TVCP. Results: 20 (91%, N=22) patients detect cTn
>1 URL after pacing. Paired t-test compare before and after
pacing leads insertion showed a mean cTn elevation of 3.599 (95% CI,
1.566 to 5.632, P<0.01)URL, and no significantly creatine
kinase-MB elevation of 0.1550 (95% CI, -0.01239 to 0.3224,
P>0.05 ) URL. Conclusion: This study demonstrates a high
incidence of substantial myocardial injury by TVCP, which should be
concerned.