Patient population
We systematically reviewed the available literature for ECGs of patients
with diLQTS and subsequent TdP. We entered the MeSH term ‘drug induced
long qt torsades de pointes’ into Medline and Embase and identified 1253
reports published until April 19th, 2020. Eligible
articles had to include human subjects with available limb ECG leads
with drug-induced QT interval prolongation and experiencing subsequent
TdP. We also screened the references of eligible papers. After manual
review, we identified 77 ECGs that were included in the current study.
We also reviewed eligible ECGs with the same criteria from the hospital
files of our institution (Hospital Haut-Leveque, University Hospital
Bordeaux, Pessac, France) and furthermore included 7 patients.