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What is new in drug hypersensitivity in children?
  • Marina Atanaskovic-Markovic
Marina Atanaskovic-Markovic
University of Belgrade Faculty of Medicine

Corresponding Author:marinaamarkovic@gmail.com

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Abstract

This review highlights the novelties in understanding the underlying immunological mechanisms of drug hypersensitivity reactions (DHRs) as well as tiny changes in clinical classification and diagnosis of DHRs with special reference to beta-lactams (BLs) in the pediatric population, in the last couple of years. Viral infections are very often in children and they can provoke skin rashes which is difficult to differentiate from DHRs. Because of that allergy to BLs in children is overdiagnosed. The correct diagnosis of BLs allergy in children is still an important and hot topic. In this review has been outlined the need for correct diagnosis of BLs allergy in children as well as needed to change the paradigm.
14 May 2020Submitted to Pediatric Allergy and Immunology
18 May 2020Reviewer(s) Assigned
08 Jun 2020Review(s) Completed, Editorial Evaluation Pending
09 Jun 2020Editorial Decision: Revise Major
11 Jul 20201st Revision Received
14 Jul 2020Review(s) Completed, Editorial Evaluation Pending
12 Aug 2020Editorial Decision: Accept