Respiratory depression as side effect: should benzodiazepines be avoided
in patients with COVID-19?
- Sander Borgsteede,
- Klaas Van Kralingen,
- Janwillem Kocks
Sander Borgsteede
Health Base Foundation
Corresponding Author:sander.borgsteede@healthbase.nl
Author ProfileAbstract
The pharmacological profile of benzodiazepines includes respiratory
depression, and theoretically benzodiazepines might contribute to
respiratory dysfunction. There are currently no data that indicate that
benzodiazepines are problematic in COVID-19, and the risk is expected to
be limited. Benzodiazepines are effective and frequently used, and if
there is a clear indication in patients with COVID-19 there is
insufficient reason to avoid benzodiazepines based on respiratory
depression as side effect.