Spontaneous myocardial infarction (double-arm randomised and observational studies)
Comparing the results of two randomised control studies12,13 with a total of 269 patients, we noted no significant difference in the rates of spontaneous MI associated with the use of FFR-guided CABG vs. CAG-guided CABG. (RR: 0.70, 95% CI: 0.08 to 6.25, p = 0.75) (Figure 3D). Data analysis of 2 observational studies14,15 and 1023 patients showed again no significant difference in the need of target vessel revascularisation with the use of either FFR-guided CABG or CAG-guided CABG (RR: 0.77, 95% CI: 0.47 to 1.25, p = 0.29) (Figure 3D). Likewise in all four studies with a total of 1292 patients, there was no difference in the rates of spontaneous MI in the FFR-guided CABG group and the CAG-guided CABG group (RR: 0.77, 95% CI: 0.48 to 1.23, p = 0.27) (Figure 3D).