In all patients, regardless of associated comorbidity,
Patients should have at least moderate symptoms measured on the SNOT-22 (>20) or VAS scale (>3) on current treatment, and a Lund-Mackay score of 8 or more to be considered for a biologic
Biologics should NOT be considered if the patient has not used corticosteroids in any form in the preceding 12 months.
Biologics should be considered if patients have received 2 or more courses of OCS, or are unable to take OCS AND have had 3 or more surgeries, or are considered unfit for surgery (under local or general anaesthetic)