Conclusion
This case highlights the importance of early suspicion ofCryptococcus neoformans infection and other opportunistic
infections in immunocompromised patients, putting in mind that patients
with Cryptococcaemia have a high risk of mortality within 30 days, which
warrants the use of corticosteroid and immunomodulatory drugs in a
critically ill patient with COVID-19. In the current scenario, the use
of immunosuppressive therapy should be justified and to be alert for
opportunistic infection like Cryptococcus neoformans infection,
which can lead to sepsis and mortality.