Pheochromocytoma is a rare catecholamine-secreting tumor derived from chromaffin cells in the adrenal glands. A pheochromocytoma ‘crisis’ (PCC) can cause haemodynamic instability and end-organ damage or dysfunction. An excessive stimulation of cardiac myocytes could lead to myocardial damage with cardiogenic shock (CS). Use of mechanical circulatory support (MCS) might find an indication in this scenario as a bridge to myocardial recovery. We present the case of a patient successfully supported with ECMO (ExtraCorporeal Membrane Oxygenation) combined with IMPELLA CP heart pump (Abiomed Danvers, MA), for left ventricular (LV) unloading. MCS was used to favour myocardial recovery and avoid cardiac remodeling.