References
Ahuja, C. S., Nori, S., Tetreault, L., Wilson, J., Kwon, B., Harrop, J., Choi, D., & Fehlings, M. G. (2017). Traumatic Spinal Cord Injury—Repair and Regeneration. Neurosurgery , 80 (3S), S9–S22. https://doi.org/10.1093/neuros/nyw080
Au, W. W., Treloar, H. B., & Greer, C. A. (2002). Sublaminar organization of the mouse olfactory bulb nerve layer. The Journal of Comparative Neurology , 446 (1), 68–80. http://www.ncbi.nlm.nih.gov/pubmed/11920721
Badenes, S. M., Fernandes, T. G., Miranda, C. C., Pusch-Klein, A., Haupt, S., Rodrigues, C. A., Diogo, M. M., Brüstle, O., & Cabral, J. M. (2017). Long-term expansion of human induced pluripotent stem cells in a microcarrier-based dynamic system. Journal of Chemical Technology & Biotechnology , 92 (3), 492–503. https://doi.org/10.1002/jctb.5074
Bianco, J. I., Perry, C., Harkin, D. G., Mackay-Sim, A., & Féron, F. (2004). Neurotrophin 3 promotes purification and proliferation of olfactory ensheathing cells from human nose. Glia , 45 (2), 111–123. https://doi.org/10.1002/glia.10298
Bickenbach, J., Office, A., Shakespeare, T., & von Groote, P. (2013).International perspectives on spinal cord injury . World Health Organization.
Casarosa, S., Bozzi, Y., & Conti, L. (2014). Neural stem cells: ready for therapeutic applications? Molecular and Cellular Therapies ,2 (1), 31. https://doi.org/10.1186/2052-8426-2-31
Chen, T., Arslan, F., Yin, Y., Tan, S., Lai, R., Choo, A., Padmanabhan, J., Lee, C., de Kleijn, D. P., & Lim, S. (2011). Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs. Journal of Translational Medicine , 9 (1), 47. https://doi.org/10.1186/1479-5876-9-47
Daud, M. F. B., Pawar, K. C., Claeyssens, F., Ryan, A. J., & Haycock, J. W. (2012). An aligned 3D neuronal-glial co-culture model for peripheral nerve studies. Biomaterials , 33 (25), 5901–5913. https://doi.org/10.1016/j.biomaterials.2012.05.008
Delorme, B., Nivet, E., Gaillard, J., Häupl, T., Ringe, J., Devèze, A., Magnan, J., Sohier, J., Khrestchatisky, M., Roman, F. S., Charbord, P., Sensebé, L., Layrolle, P., & Féron, F. (2010). The Human Nose Harbors a Niche of Olfactory Ectomesenchymal Stem Cells Displaying Neurogenic and Osteogenic Properties. Stem Cells and Development , 19 (6), 853–866. https://doi.org/10.1089/scd.2009.0267
dos Santos, F., Campbell, A., Fernandes-Platzgummer, A., Andrade, P. Z., Gimble, J. M., Wen, Y., Boucher, S., Vemuri, M. C., da Silva, C. L., & Cabral, J. M. S. (2014). A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells.Biotechnology and Bioengineering , 111 (6), 1116–1127. https://doi.org/10.1002/bit.25187
Doucette, J. R. (1984). The glial cells in the nerve fiber layer of the rat olfactory bulb. The Anatomical Record , 210 (2), 385–391. https://doi.org/10.1002/ar.1092100214
Doucette, R. (1991). PNS-CNS transitional zone of the first cranial nerve. The Journal of Comparative Neurology , 312 (3), 451–466. https://doi.org/10.1002/cne.903120311
Féron, F., Mackay-Sim, A., Andrieu, J. ., Matthaei, K. ., Holley, A., & Sicard, G. (1999). Stress induces neurogenesis in non-neuronal cell cultures of adult olfactory epithelium. Neuroscience ,88 (2), 571–583. https://doi.org/10.1016/S0306-4522(98)00233-4
Féron, F., Perry, C., Cochrane, J., Licina, P., Nowitzke, A., Urquhart, S., Geraghty, T., & Mackay-Sim, A. (2005). Autologous olfactory ensheathing cell transplantation in human spinal cord injury.Brain , 128 (12), 2951–2960. https://doi.org/10.1093/brain/awh657
Franceschini, I. A., & Barnett, S. C. (1996). Low-Affinity NGF-Receptor and E-N-CAM Expression Define Two Types of Olfactory Nerve Ensheathing Cells That Share a Common Lineage. Developmental Biology ,173 (1), 327–343. https://doi.org/10.1006/dbio.1996.0027
Hahn, C.-G., Han, L.-Y., Rawson, N. E., Mirza, N., Borgmann-Winter, K., Lenox, R. H., & Arnold, S. E. (2005). In vivo and in vitro neurogenesis in human olfactory epithelium. The Journal of Comparative Neurology , 483 (2), 154–163. https://doi.org/10.1002/cne.20424
Iwatsuki, K., Yoshimine, T., Kishima, H., Aoki, M., Yoshimura, K., Ishihara, M., Ohnishi, Y., & Lima, C. (2008). Transplantation of olfactory mucosa following spinal cord injury promotes recovery in rats.NeuroReport , 19 (13), 1249–1252. https://doi.org/10.1097/WNR.0b013e328305b70b
Jones, W., & Bianchi, K. (2015). Aerobic Glycolysis: Beyond Proliferation. Frontiers in Immunology , 6 . https://doi.org/10.3389/fimmu.2015.00227
Jonsson, S., Wiberg, R., McGrath, A. M., Novikov, L. N., Wiberg, M., Novikova, L. N., & Kingham, P. J. (2013). Effect of Delayed Peripheral Nerve Repair on Nerve Regeneration, Schwann Cell Function and Target Muscle Recovery. PLoS ONE , 8 (2), e56484. https://doi.org/10.1371/journal.pone.0056484
Kawaja, M. D., Boyd, J. G., Smithson, L. J., Jahed, A., & Doucette, R. (2009). Technical Strategies to Isolate Olfactory Ensheathing Cells for Intraspinal Implantation. Journal of Neurotrauma , 26 (2), 155–177. https://doi.org/10.1089/neu.2008.0709
Lindsay, S. L., Johnstone, S. A., Mountford, J. C., Sheikh, S., Allan, D. B., Clark, L., & Barnett, S. C. (2013). Human mesenchymal stem cells isolated from olfactory biopsies but not bone enhance CNS myelination in vitro. Glia , 61 (3), 368–382. https://doi.org/10.1002/glia.22440
Mackay-Sim, A., Feron, F., Cochrane, J., Bassingthwaighte, L., Bayliss, C., Davies, W., Fronek, P., Gray, C., Kerr, G., Licina, P., Nowitzke, A., Perry, C., Silburn, P. A. S., Urquhart, S., & Geraghty, T. (2008). Autologous olfactory ensheathing cell transplantation in human paraplegia: a 3-year clinical trial. Brain , 131 (9), 2376–2386. https://doi.org/10.1093/brain/awn173
Meijering, E., Jacob, M., Sarria, J.-C. F., Steiner, P., Hirling, H., & Unser, M. (2004). Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy images. Cytometry ,58A (2), 167–176. https://doi.org/10.1002/cyto.a.20022
Murrell, W., Féron, F., Wetzig, A., Cameron, N., Splatt, K., Bellette, B., Bianco, J., Perry, C., Lee, G., & Mackay-Sim, A. (2005). Multipotent stem cells from adult olfactory mucosa. Developmental Dynamics , 233 (2), 496–515. https://doi.org/10.1002/dvdy.20360
Nash, H. H., Borke, R. C., & Anders, J. J. (2001). New method of purification for establishing primary cultures of ensheathing cells from the adult olfactory bulb. Glia , 34 (2), 81–87. https://doi.org/10.1002/glia.1043
Oh, S. K. W., Chen, A. K., Mok, Y., Chen, X., Lim, U.-M., Chin, A., Choo, A. B. H., & Reuveny, S. (2009). Long-term microcarrier suspension cultures of human embryonic stem cells. Stem Cell Research ,2 (3), 219–230. https://doi.org/10.1016/j.scr.2009.02.005
Pixley, S. K. (1992). The olfactory nerve contains two populations of glia, identified both in vivo and in vitro. Glia , 5 (4), 269–284. https://doi.org/10.1002/glia.440050405
Qiu, L., Lim, Y. M., Chen, A. K., Reuveny, S., Oh, S. K. W., Tan, E. K., & Zeng, L. (2016). Microcarrier-Expanded Neural Progenitor Cells Can Survive, Differentiate, and Innervate Host Neurons Better When Transplanted as Aggregates. Cell Transplantation , 25 (7), 1343–1357. https://doi.org/10.3727/096368915X690378
Rafiq, Q. A., Brosnan, K. M., Coopman, K., Nienow, A. W., & Hewitt, C. J. (2013). Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor. Biotechnology Letters , 35 (8), 1233–1245. https://doi.org/10.1007/s10529-013-1211-9
Rafiq, Q. A., Coopman, K., Nienow, A. W., & Hewitt, C. J. (2016). Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors.Biotechnology Journal , 11 (4), 473–486. https://doi.org/10.1002/biot.201400862
Ramon-Cueto, A., Perez, J., & Nieto-Sampedro, M. (1993). In vitro enfolding of olfactory neurites by p75 NGF receptor positive ensheathing cells from adult rat olfactory bulb. Eur J Neurosci , 5 (9), 1172–1180.
Rodrigues, Carlos AV, Silva, T. P., Nogueira, D. E., Fernandes, T. G., Hashimura, Y., Wesselschmidt, R., Diogo, M. M., Lee, B., & Cabral, J. M. (2018). Scalable culture of human induced pluripotent cells on microcarriers under xeno-free conditions using single-use vertical-wheelTM bioreactors. Journal of Chemical Technology & Biotechnology . https://doi.org/10.1002/jctb.5738
Rodrigues, Carlos A. V., Diogo, M. M., da Silva, C. L., & Cabral, J. M. S. (2011). Microcarrier expansion of mouse embryonic stem cell-derived neural stem cells in stirred bioreactors. Biotechnology and Applied Biochemistry , 58 (4), 231–242. https://doi.org/10.1002/bab.37
Santiago-Toledo, G., Georgiou, M., dos Reis, J., Roberton, V. H., Valinhas, A., Wood, R. C., Phillips, J. B., Mason, C., Li, D., Li, Y., Sinden, J. D., Choi, D., Jat, P. S., & Wall, I. B. (2019). Generation of c-MycERTAM-transduced human late-adherent olfactory mucosa cells for potential regenerative applications. Scientific Reports ,9 (1), 1–13. https://doi.org/10.1038/s41598-019-49315-6
Santos, F. dos, Andrade, P. Z., Abecasis, M. M., Gimble, J. M., Chase, L. G., Campbell, A. M., Boucher, S., Vemuri, M. C., Silva, C. L. da, & Cabral, J. M. S. (2011). Toward a Clinical-Grade Expansion of Mesenchymal Stem Cells from Human Sources: A Microcarrier-Based Culture System Under Xeno-Free Conditions. Tissue Engineering Part C: Methods , 17 (12), 1201–1210. https://doi.org/10.1089/ten.tec.2011.0255
Schop, D., Janssen, F. W., van Rijn, L. D. S., Fernandes, H., Bloem, R. M., de Bruijn, J. D., & van Dijkhuizen-Radersma, R. (2009). Growth, Metabolism, and Growth Inhibitors of Mesenchymal Stem Cells.Tissue Engineering Part A , 15 (8), 1877–1886. https://doi.org/10.1089/ten.tea.2008.0345
Shim, H., Chun, Y. S., Lewis, B. C., & Dang, C. V. (1998). A unique glucose-dependent apoptotic pathway induced by c-Myc. Proceedings of the National Academy of Sciences , 95 (4), 1511–1516. https://doi.org/10.1073/pnas.95.4.1511
Tabakow, P., Jarmundowicz, W., Czapiga, B., Fortuna, W., Miedzybrodzki, R., Czyz, M., Huber, J., Szarek, D., Okurowski, S., Szewczyk, P., Gorski, A., & Raisman, G. (2013). Transplantation of Autologous Olfactory Ensheathing Cells in Complete Human Spinal Cord Injury.Cell Transplantation , 22 (9), 1591–1612. https://doi.org/10.3727/096368912X663532
Wall, I. B., Santiago Toledo, G., & Jat, P. S. (2016). Recent advances in conditional cell immortalization technology. Cell and Gene Therapy Insights , 2 (3), 391–396. https://doi.org/10.18609/cgti.2016.041
Wolozin, B., Sunderland, T., Zheng, B., Resau, J., Dufy, B., Barker, J., Swerdlow, R., & Coon, H. (1992). Continuous culture of neuronal cells from adult human olfactory epithelium. Journal of Molecular Neuroscience , 3 (3), 137–146. https://doi.org/10.1007/BF02919405
Yang, Y., Wang, K., Gu, X., & Leong, K. W. (2017). Biophysical Regulation of Cell Behavior—Cross Talk between Substrate Stiffness and Nanotopography. Engineering , 3 (1), 36–54. https://doi.org/10.1016/J.ENG.2017.01.014