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What do we know about Mirror Syndrome? -- a comprehensive review
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  • Ayssa Teles Abrao Trad,
  • Ricardo Czeresnia,
  • Amro Elrefaei,
  • Eniola Ibirogba,
  • Kavita Narang,
  • Rodrigo Ruano
Ayssa Teles Abrao Trad
Mayo Clinic

Corresponding Author:telesabraotrad.ayssa@mayo.edu

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Ricardo Czeresnia
Irmandade da Santa Casa de Misericordia de Sao Paulo
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Amro Elrefaei
Mayo Clinic
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Eniola Ibirogba
Mayo Clinic
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Kavita Narang
Mayo Clinic
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Rodrigo Ruano
Mayo Clinic
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Abstract

Mirror syndrome is a rare disease associated with a high fetal mortality of up to 67.2%. It is thought to be underdiagnosed and is often mistaken for preeclampsia. Mirror syndrome is characterized by ‘triple edema’: generalized maternal, placental, and fetal edema. A comprehensive search of several databaseswas conducted. Mirror syndrome is associated with high fetal morbidity and mortality; it is an important differential diagnosis with pre-eclampsia and thought to be currently underdiagnosed. Minimal is known about its pathogenesis. Maternal symptoms usually regress with resolution of pregnancy and management is dependent on the cause of fetal hydrops.