Introduction
Psoriasis is a chronic inflammatory disease caused by hyperproliferation
of the keratinocytes in the epidermis [1]. The pathophysiology of
psoriasis still remains uncertain; however, it appears to be influenced
by genetic and immune-mediated components [2]. This is supported by
the successful treatment of psoriasis by immune mediating medications
and the increase in the number of activated T-cells in the dermis that
are capable of inducing proliferation of the keratinocytes [3-5].
Previous studies have discovered an association between specific HLA
antigens and gene deletions with the susceptibility to psoriasis in
different populations [6]. There are various types of psoriasis
including plaque-type psoriasis, guttate psoriasis, pustular psoriasis,
linear psoriasis and more [7]. Here, we report the first case of
dermatomal psoriasis and a case of unusual plaque psoriasis in two
different patients.