Therapeutic strategies to fight COVID-19: which is the status artis?
- Cristina Scavone,
- Annamaria Mascolo,
- Concetta Rafaniello,
- Liberata Sportiello,
- Ugo Trama,
- Alice Zoccoli,
- Francesca Bernardi,
- Giorgio Racagni,
- Liberato Berrino,
- Giuseppe Castaldo,
- Enrico Coscioni,
- Francesco Rossi,
- Annalisa Capuano
Cristina Scavone
Università degli Studi della Campania Luigi Vanvitelli
Corresponding Author:cristina.scavone@unicampania.it
Author ProfileAnnamaria Mascolo
Università degli Studi della Campania Luigi Vanvitelli
Author ProfileConcetta Rafaniello
Università degli Studi della Campania Luigi Vanvitelli
Author ProfileLiberata Sportiello
Università degli Studi della Campania Luigi Vanvitelli
Author ProfileEnrico Coscioni
Agenzia Nazionale per i Servizi Sanitari Regionali
Author ProfileFrancesco Rossi
Università degli Studi della Campania Luigi Vanvitelli
Author ProfileAnnalisa Capuano
Università degli Studi della Campania Luigi Vanvitelli
Author ProfileAbstract
COVID-19 is a complex disease and many difficulties are faced today
especially in the proper choice of pharmacological treatments. The role
of antiviral agents for COVID-19 is still being investigated. The
evidence for immunomodulatory and anti-inflammatory drugs is quite
conflicting, while the use of corticosteroids is supported by robust
evidence. The use of heparins in hospitalized critically ill patients is
preferred over other anticoagulants. Lastly, conflicting data were found
regarding to the use of convalescent plasma and vitamin D. According to
data shared by the WHO, many vaccines are under phase 3 clinical trials
and some of them already received the marketing approval in EU countries
and in the US. In conclusion, drugs repurposing has represented the main
approach recently used in the treatment of patients with COVID-19. At
this moment, the analysis of efficacy and safety data of drugs and
vaccines used in real life context is strongly needed.13 Jan 2021Submitted to British Journal of Pharmacology 17 Jan 2021Submission Checks Completed
17 Jan 2021Assigned to Editor
18 Jan 2021Reviewer(s) Assigned
31 Jan 2021Review(s) Completed, Editorial Evaluation Pending
01 Feb 2021Editorial Decision: Revise Minor
12 Feb 20211st Revision Received
15 Feb 2021Submission Checks Completed
15 Feb 2021Assigned to Editor
15 Feb 2021Reviewer(s) Assigned
27 Feb 2021Review(s) Completed, Editorial Evaluation Pending
28 Feb 2021Editorial Decision: Revise Minor
01 Mar 20212nd Revision Received
03 Mar 2021Submission Checks Completed
03 Mar 2021Assigned to Editor
04 Mar 2021Review(s) Completed, Editorial Evaluation Pending
05 Mar 2021Editorial Decision: Accept
May 2022Published in British Journal of Pharmacology volume 179 issue 10 on pages 2128-2148. 10.1111/bph.15452