TABLE 2 : A selection of amino acid positions in the 2930 PETase
homologues from the LED. Amino acid residues that occurred in less than
50% of the sequences are listed in brackets for comparison with their
previous mentions in literature. Amino acid substitutions “in LCC”
refer to the position numbers used in 40. Some
positions only occurred in a small subset of all PETase homologues and
are thus indicated as gap symbols (-). Percentages indicate values
rounded to integers. Sixteen positions and their corresponding amino
acid symbols marked in red indicate the suggested PETase sequence motif,
whereas the ones marked in green indicate additional positions that were
used to select the sequences mentioned in the main text.