Domain Analysis
BLK kinase has 3 domains named SH3 domain, SH2 domain, Protein Tyrosine Kinase was located in a region of 64 – 110, 124 – 205, 241 – 490 respectively. We have used Pfam server (El-Gebali et al., 2019) for the domain analysis. We have also checked for glycosylation site on blk using NetNGlyc 1.0 Server (Gupta, Jung, & Brubak, 2004) which shows there is not glycosylation site on BLK. We have also plotted all 3 domains of the BLK along with the secondary structure and sequence representation for better understanding (Fig. 10).
Fig. 10 Predicted domains on BLK