Search, screen, and selection of SCD in pregnancy CPGs
We used literature searches of bibliographic databases (Medline/PubMed and Google Scholar), EBSCO DynaMed Plus (USA), and relevant CPG databases: the ECRI Institute Guidelines Trust, National Institute of Health and Care Excellence (NICE; UK), Guidelines International Network (G-I-N) International guideline library, Scottish Intercollegiate Guidelines Network (SIGN; UK), and the Australian National Health and Medical Research Council (NHMRC; Australia). Moreover, we searched databases of national and international societies specializing in fields related to our health topic of SCD in pregnancy like the American College of Obstetricians and Gynecologists (ACOG), Royal College of Obstetricians and Gynaecologists (RCOG), Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG), Society for Maternal Fetal Medicine (SMFM), Saudi Society for Obstetrics and Gynecology (SSOG), and Arab Association of Obstetrics and Gynaecology Societies (FAGOS). Keywords used included “sickle cell disease” AND “pregnancy” OR “pregnant women” AND “guideline,” “practice guideline,” “clinical practice guideline,” “practice parameter,” “guidance,” OR “recommendations”.11
The PubMed electronic search strategy included; (”anemia, sickle cell”[MeSH Terms] OR (”anemia”[All Fields] AND ”sickle”[All Fields] AND ”cell”[All Fields]) OR ”sickle cell anemia”[All Fields] OR (”sickle”[All Fields] AND ”cell”[All Fields] AND ”disease”[All Fields]) OR ”sickle cell disease”[All Fields]) AND ”pregnan”[All Fields] AND (”pregnancy”[MeSH Terms] OR ”pregnancy”[All Fields]) OR (”pregnant women”[MeSH Terms] OR (”pregnant”[All Fields] AND ”women”[All Fields]) OR ”pregnant women”[All Fields]) AND (”guideline”[Publication Type] OR ”guidelines as topic”[MeSH Terms] OR ”guidelines”[All Fields]) AND (Practice Guideline[ptyp] AND (”2014/01/01”[PDAT] : ”2019/12/31”[PDAT]) AND ”humans”[MeSH Terms]). Furthermore, we used the PIPOH (Patient Population, Interventions, Professionals, Outcomes, and Healthcare Setting) model to support the CPG eligibility process.10 Three reviewers (YA, MA, YS) screened titles and abstracts of retrieved CPGs and articles meeting the inclusion criteria independently. The screening was re-checked by three different reviewers (GE, AA, OK). Disagreements were resolved by focus group discussions within the whole group after retrieval and review of the full-text articles or full CPG documents, including links to any accessible online supplementary documents or web resources. The search was repeated before the final manuscript submission to retrieve any new eligible CPG.