NA – not applicable
Table 2: Viral clearance by Eshmuno Q anion exchange chromatography
using different loading and spiking methods. Experiments were performed
in product flow-through mode in Tris-HCl buffer (pH 8.5 and conductivity
6 mS/cm); residence time was maintained at 4 min for all runs. Each run
was spiked with a total of approximately 8 log10TCID50 MMV. The flow through pool represents the virus
present in the pooled four flow through fractions and wash fraction. The
data represent the mean of two runs.