This is a review of the preprint "Cell boundary confinement sets the size and position of the E. coli chromosome" by Fabai Wu, Pinaki Swain, Louis Kuijpers, Xuan Zheng, Kevin Felter, Margot Guurink, Debasish Chaudhuri, Bela Mulder and Cees Dekker. The article was posted on bioRxiv on 15 June 2018 (https://doi.org/10.1101/348052). The ITQB Preprint Journal club reviewed the article on 3 July 2018. This review was written by Dr. Ambre Jousselin, who led the Preprint Journal Club. Dr. Manuel Melo made major contributions to analysis of simulations, and Dr. Zach Hensel helped edit the review for posting on PREreview and commented on microscopy methods.