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\begin{document}
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\title{Intelligence GWAS hits: Selection signal or population structure? A test
of the null hypothesis}



\author[1]{Davide Piffer}%
\affil[1]{Affiliation not available}%


\vspace{-1em}



  
  \date{May 08, 2026}


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\begin{abstract}
An index of population structure (Fst) is used to test the null
hypothesis that the genetic factor extracted from GWAS hits represents
differences between populations due to migrations and drift. Employing
the 1000 Genomes data, a regression of average IQ distances on the
general intelligence genetic factor and Fst distances shows that the
former is the only significant predictor of IQ distances(Beta= 0.82),
whereas the population structure has no independent predictive power
(Beta=-0.05). This result suggests that the null hypothesis can be
rejected.%
\end{abstract}%



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