Detection of urinary tract infection in a child with chronic kidney disease by metagenomic sequencingShort running title: UTI detection in CKD by metagenomicsAuthors: Yeping Jiang, Ting Wang, Jia Liu, Yunhua Zhao, Jingfang SongAffiliation: Department of Nephrology, Baoding Hospital of Beijing Children’s Hospital, Capital Medical UniversityCorresponding Author: Yeping JiangE-mail: jiangyeping@mail.ccmu.edu.cnConflict of Interest: The authors declare no conflicts of interest.Ethical Approval : This study was approved by the Ethics Committee of Baoding Hospital of Beijing Children’s Hospital, Capital Medical UniversityInformed Consent : Written informed consent for both study participation and publication of this case report was obtained from the child’s legal guardian prior to study initiation.Key Clinical Message (KCM) : Metagenomic sequencing identified Ureaplasma urealyticum and Candida parapsilosis in a stage 5 CKD child with VUR and negative routine cultures, enabling targeted treatment for refractory UTI.