Title PageTitle: A concise, informative title that avoids jargon and includes the name of the organism under study,Authors Names: For the authors' names, indicate different affiliations with the superscript symbols: *, †, ‡, §. (These symbols can be inserted using Microsoft Word.) After four authors, the symbols double, triple, quadruple, etc., but in the same order ( **, ††, ‡‡, §§)Use a numbered footnote to indicate an author's present address. Indicate a dedicatory footnote (if desired) with boldfaced type.Affiliations: the authors' institutional affiliations, including department; institution; and city, state or province, country if outside the United States, and postal code (do not include districts or street addresses).Reference numbers: for data available in public repositories and IRB numbers.

The name(s) of the author(s):A concise and informative title:The affiliation(s) and address(es) of the author(s):The e-mail address, and telephone number(s) of the corresponding author:If available, the 16-digit ORCID of the author(s):Abstract:Please provide an abstract of 150 to 250 words. The abstract should not contain any undefined abbreviations or unspecified references.KeywordsPlease provide 4 to 6 keywords which can be used for indexing purposes.

This example manuscript is intended to serve as a tutorial and template for authors to use when writing their own AAS Journal articles. The manuscript includes a history of   and documents the new features in the previous version, 6.0, as well as the new features in version 6.1. This manuscript includes many figure and table examples to illustrate these new features. Information on features not explicitly mentioned in the article can be viewed in the manuscript comments or more extensive online documentation. Authors are welcome replace the text, tables, figures, and bibliography with their own and submit the resulting manuscript to the AAS Journals peer review system. The first lesson in the tutorial is to remind authors that the AAS Journals, the Astrophysical Journal (ApJ), the Astrophysical Journal Letters (ApJL), and Astronomical Journal (AJ), all have a 250 word limit for the abstract. If you exceed this length the Editorial office will ask you to shorten it.

The arXiv is the most popular preprint repository in the world. Since its inception in 1991, the arXiv has allowed researchers to freely share publication-ready articles prior to formal peer review. The growth and the popularity of the arXiv emerged as a result of new technologies that made document creation and dissemination easy, and cultural practices that incentivized collaboration and data sharing. The arXiv represents a unique place in the history of research communication and the Web itself, however it has arguably changed very little since its creation.  Here we look at the strengths and weaknesses of arXiv in an effort to identify what possible improvements can be made based on new technologies not previously available. Based on this, we argue that a modern arXiv might in fact not look at all like the arXiv of today.  

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Pellentesque tincidunt lobortis orci non venenatis. Cras in justo luctus, pulvinar augue id, suscipit diam. Morbi aliquet fringilla nibh, vel pellentesque dui venenatis eget. Orci varius natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Donec ultricies ultrices magna gravida porta. Maecenas accumsan diam dui, auctor ornare ex pellentesque id. Integer tempus massa id augue finibus convallis. Nulla vestibulum, nisl id tempor pulvinar, felis dui pellentesque lacus, quis bibendum metus enim sed ex.

Title PageAbbreviated title (50 character max): SfN Mock ArticleAuthor Names and Affiliations:  Pete D. Nicholson\(^1\), Alberto Pepe\(^1\)\(^1\): Authorea, Brooklyn, NY 11249Number of pages: 6Number of figures: 2Number of WordsAbstract: 147Introduction: 27Discussion: 504Conflict of interest statement: The authors declare no competing financial interests.Acknowledgements: None

Abstract (250 Words Maximum)Lorem ipsum dolor sit amet, consectetur adipiscing elit. Duis vestibulum diam a eleifend tincidunt. Class aptent taciti sociosqu ad litora torquent per conubia nostra, per inceptos himenaeos. Morbi libero risus, pretium ac urna vel, iaculis sagittis nisl. Duis non sapien justo. Quisque elementum, mauris a ullamcorper pharetra, mauris enim ullamcorper urna, sit amet fermentum sem nulla vel nibh. Etiam id urna non leo condimentum egestas pulvinar sit amet ex. Aenean faucibus eget dui at gravida. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Vestibulum sodales neque dolor, et mollis turpis viverra non. Sed quam libero, ornare vitae rutrum eu, venenatis et massa. Morbi rutrum vulputate tellus, sit amet placerat arcu fringilla et. Vestibulum condimentum blandit libero eget luctus. Sed suscipit accumsan nibh vel lobortis. Maecenas tellus mi, commodo id odio nec, ullamcorper rutrum neque. Duis tincidunt ut tellus ut sodales. Aenean in massa ac ligula scelerisque viverra.Significance Statement (120 Words Maximum)retra mauris enim ullamcorper urna sit amet fermentum sem nulla vel nibh. Etiam id urna non leo condimentum egestas pulvinar sit amet ex. Aenean faucibus eget dui at gravida. Lorem ipsum dolor sit amet consectetur adipiscing elit. VestiIntroduction (750 Words Maximum)The Introduction should briefly indicate the objectives of the study and provide enough background information to clarify why the study was undertaken and what hypotheses were tested.Materials and MethodsThe materials and methods section should be brief but sufficient to allow other investigators to repeat the research (see also Policy Concerning Availability of Materials). Reference should be made to published procedures wherever possible; this applies to the original description and pertinent published modifications. The sex of subjects should be stated. If the sex of subjects is unknown, this should be stated. All companies from which materials were obtained should be listed. If materials were obtained from an individual, an affiliation for that individual should be listed. A manuscript that presents only a theory may omit the Materials and Methods section.Experimental DesignDescription of experimental design retra mauris enim ullamcorper urna sit amet fermentum sem nulla vel nibh. Etiam id urna non leo condimentum egestas pulvinar sit amet ex. Aenean faucibus eget dui at gravida. Lorem ipsum dolor sit amet consectetur adipiscing elit. VestiStatistical AnalysisDescription of statistical analysis retra mauris enim ullamcorper urna sit amet fermentum sem nulla vel nibh. Etiam id urna non leo condimentum egestas pulvinar sit amet ex. Aenean faucibus eget dui at gravida. Lorem ipsum dolor sit amet consectetur adipiscing elit. VestiResultsLorem ipsum dolor sit amet consectetur adipiscing elit. Duis vestibulum diam a eleifend tincidunt. Class aptent taciti sociosqu ad litora torquent per conubia nostra per inceptos himenaeos. Morbi libero risus pretium ac urna vel iaculis sagittis nisl. Duis non sapien justo. Quisque elementum mauris a ullamcorper pharetra mauris enim ullamcorper urna sit amet fermentum sem nulla vel nibh. Etiam id urna non leo (Figure \ref{333327}) condimentum egestas pulvinar sit amet ex. Aenean faucibus eget dui at gravida. Lorem ipsum dolor sit amet consectetur adipiscing elit. Vestibulum sodales neque dolor et mollis turpis viverra non. Sed quam libero ornare vitae rutrum eu venenatis et massa. Morbi rutrum vulputate tellus sit amet placerat arcu fringilla et. Vestibulum condimentum blandit libero eget luctus. Sed suscipit accumsan nibh vel lobortis. Maecenas tellus mi commodo id odio nec ullamcorper rutrum neque. Duis tincidunt ut tellus ut sodales. Aenean in massa ac ligula scelerisque viverra.

Research ArticlesResearch Articles report on original studies with broad impact across the fields of basic, translational, clinical, and epidemiologic cancer research as well as cancer prevention research. These articles should be of exceptional significance to a diverse audience of cancer researchers and scientists.

Research ArticlesOriginal studies offering broad impact across the fields of basic, preclinical, clinical, prevention, and epidemiologic cancer research. The reports should be well-documented, novel, and significant to the field as a whole. The Editor-in-Chief and members of the senior editorial board reserve the right to edit title, abstract, and précis for articles that are accepted to improve their clarity, brevity, and quality.

Mathematical Oncology Research ArticlesPublished in the Integrated Systems and Technologies section of the journal, Mathematical Oncology articles include mathematical approaches to problems in cancer research. These articles will contain new testable hypotheses, integration of theory and experimental data, facilitation of wide-ranging investigations, and basic laws of biology. The format and length restrictions for this category of publication are as follows:

Meeting ReportsBrief reports of symposia and conferences in cancer research. Reports must be submitted within 2 months of the meeting date in order to maintain their timeliness. Only those Meeting Reports dealing with topics of interest to the readership that contain novel information and insights from the meeting will be accepted for publication. A Meeting Report should offer a thoughtful, critical commentary that shows an appreciation of the connections among various presentations and reveals the consensus, if any, that emerged on matters of importance at the meeting. Before submitting a Meeting Report for consideration, potential authors must send a letter to the attention of Dr. Mariano Barbacid, Deputy Editor for Meeting Reports, to inquire whether the suggested meeting satisfies criteria for consideration. Letters of inquiry should be sent to the Publications Office (Fax: (215) 440-9354; E-mail: cancerres@aacr.org). Length restrictions for this category of publication are as follows:100 word abstract2,500 words of textFigures and/or tables are not permitted without prior approval from the EditorsReferences, if necessary, must be kept to a minimumA statement of the purpose of the meeting, an integrated summary of the findings presented, and recommendations for future researchThe names and affiliations of key speakers should be given in an appendix that is submitted as supplemental information, not as part of the manuscript textAbstractThe abstract must be concise, yet should accurately outline the content of the manuscript (see the Categories of Articles page of each journal for abstract length requirements for each type of article). Because these abstracts are used by secondary services (e.g., MEDLINE, Chemical Abstracts, Web of Science, Scopus), they should recapitulate in abbreviated form the purpose of the study and the experimental technique, results, and data interpretations. Data such as the number of test subjects and controls, strains of animals or viruses, drug dosages and routes of administration, tumor yields and latent periods, length of observation period, and magnitude of activity should be included. Vague, general statements such as "The significance of the results is discussed" or "Some physical properties were studied" should be avoided. Important terms relevant to the content of the manuscript should be incorporated into the abstract to assist indexers and searchers. Abbreviations should be kept to an absolute minimum; however, if they are needed, they must be explained at first mention within the abstract so that it can be understood as an independent unit from the remainder of the manuscript. Do not cite references in the abstract.IntroductionThe introduction should provide a brief overview of the background and rationale for the study. It is not necessary to cite all of the background literature in the introduction. Brief reference to the most pertinent articles generally suffices to acquaint the reader with the findings of others in the field and with the problem or question that the investigation addresses. Sample citation \cite{Andor_2017}.Materials and MethodsExplanation of the experimental methods should be adequate for repetition by qualified investigators. Procedures that have been described in previous publications should not be described in detail but merely cited with appropriate references along with any modifications of the procedure. Only new and substantial modifications of previously published procedures need complete exposition. The sources of special chemicals or preparations used should be provided. Any commercial products that are mentioned should include the name of the manufacturer and catalog numbers.ResultsInclude a concise summary of the data presented in all display items (figures and tables). Excessive elaboration of data shown in display items should be avoided.DiscussionThe data should be interpreted concisely without repeating material already presented in the Results section. Speculation is permissible, but it must be well founded, and discussion of the wider implications of the findings is encouraged.AcknowledgmentsInclude the names of others contributing to the work who are not identified as authors.

Letters to the EditorIn the spirit of open scientific dialogue, the Editors invite the submission of correspondence that presents considered opinions in response to articles published in the journal. Letters to the Editor will be peer reviewed and, if found to meet the requisite publication criteria (scholarly commentary on a subject of importance and interest to the broad readership), the Letter may be sent to the author(s) of the originally published article and possibly to other interested parties for a response to be published in the same issue of the journal as the Letter. Please note that the journal will not consider Letters to the Editor regarding Cancer Research articles that were published more than 3 months prior. Correspondence concerning articles that have not been published in Cancer Research will not be considered. The length restrictions for this category of publication are as follows:400 words of text5 references, the first of which must be the citation for the original article under discussionLetters may contain figures or tables only if they show data that refute the conclusions of the originating article. Figures or tables showing unpublished data in support of the conclusions of the originating article will not be consideredInclude a title: "Running title of the original article" — LetterAbstractThe abstract must be concise, yet should accurately outline the content of the manuscript (see the Categories of Articles page of each journal for abstract length requirements for each type of article). Because these abstracts are used by secondary services (e.g., MEDLINE, Chemical Abstracts, Web of Science, Scopus), they should recapitulate in abbreviated form the purpose of the study and the experimental technique, results, and data interpretations. Data such as the number of test subjects and controls, strains of animals or viruses, drug dosages and routes of administration, tumor yields and latent periods, length of observation period, and magnitude of activity should be included. Vague, general statements such as "The significance of the results is discussed" or "Some physical properties were studied" should be avoided. Important terms relevant to the content of the manuscript should be incorporated into the abstract to assist indexers and searchers. Abbreviations should be kept to an absolute minimum; however, if they are needed, they must be explained at first mention within the abstract so that it can be understood as an independent unit from the remainder of the manuscript. Do not cite references in the abstract.IntroductionThe introduction should provide a brief overview of the background and rationale for the study. It is not necessary to cite all of the background literature in the introduction. Brief reference to the most pertinent articles generally suffices to acquaint the reader with the findings of others in the field and with the problem or question that the investigation addresses. Sample citation \cite{Andor_2017}.Materials and MethodsExplanation of the experimental methods should be adequate for repetition by qualified investigators. Procedures that have been described in previous publications should not be described in detail but merely cited with appropriate references along with any modifications of the procedure. Only new and substantial modifications of previously published procedures need complete exposition. The sources of special chemicals or preparations used should be provided. Any commercial products that are mentioned should include the name of the manufacturer and catalog numbers.ResultsInclude a concise summary of the data presented in all display items (figures and tables). Excessive elaboration of data shown in display items should be avoided.DiscussionThe data should be interpreted concisely without repeating material already presented in the Results section. Speculation is permissible, but it must be well founded, and discussion of the wider implications of the findings is encouraged.AcknowledgmentsInclude the names of others contributing to the work who are not identified as authors.

Public IssuesBrief articles on topics of interest to cancer researchers and the general public. These topics might include articles on advocacy for funding cancer research, government relations, training in the field, public education, or science education.2,000 words of textAbstractThe abstract must be concise, yet should accurately outline the content of the manuscript (see the Categories of Articles page of each journal for abstract length requirements for each type of article). Because these abstracts are used by secondary services (e.g., MEDLINE, Chemical Abstracts, Web of Science, Scopus), they should recapitulate in abbreviated form the purpose of the study and the experimental technique, results, and data interpretations. Data such as the number of test subjects and controls, strains of animals or viruses, drug dosages and routes of administration, tumor yields and latent periods, length of observation period, and magnitude of activity should be included. Vague, general statements such as "The significance of the results is discussed" or "Some physical properties were studied" should be avoided. Important terms relevant to the content of the manuscript should be incorporated into the abstract to assist indexers and searchers. Abbreviations should be kept to an absolute minimum; however, if they are needed, they must be explained at first mention within the abstract so that it can be understood as an independent unit from the remainder of the manuscript. Do not cite references in the abstract.IntroductionThe introduction should provide a brief overview of the background and rationale for the study. It is not necessary to cite all of the background literature in the introduction. Brief reference to the most pertinent articles generally suffices to acquaint the reader with the findings of others in the field and with the problem or question that the investigation addresses. Sample citation \cite{Andor_2017}.Materials and MethodsExplanation of the experimental methods should be adequate for repetition by qualified investigators. Procedures that have been described in previous publications should not be described in detail but merely cited with appropriate references along with any modifications of the procedure. Only new and substantial modifications of previously published procedures need complete exposition. The sources of special chemicals or preparations used should be provided. Any commercial products that are mentioned should include the name of the manufacturer and catalog numbers.ResultsInclude a concise summary of the data presented in all display items (figures and tables). Excessive elaboration of data shown in display items should be avoided.DiscussionThe data should be interpreted concisely without repeating material already presented in the Results section. Speculation is permissible, but it must be well founded, and discussion of the wider implications of the findings is encouraged.AcknowledgmentsInclude the names of others contributing to the work who are not identified as authors.

PerspectivesArticles that present fresh insights on a very active or underdeveloped area of research, with a personal viewpoint on the area, its pressing issues, or its development.

ReviewsArticles that review a timely subject important to cancer researchers. Reviews must be written as concisely as possible. Authors of unsolicited Review Articles must first submit an outline of the proposed article for consideration. The outline should be sent to the attention of Dr. Danny R. Welch, Deputy Editor for Reviews (Fax: (215) 440-9354; E-mail: cancerres@aacr.org). All Review Articles, whether invited or not, will be subject to peer review. The length restrictions for this category of publication are provided below. Longer reviews will be considered only at the discretion of the Deputy Editor for Reviews.

Priority ReportsShort, definitive reports of findings of high impact, significance, and timeliness. These reports receive an accelerated review. Papers submitted as Priority Reports should include a section for Materials and Methods as well as Results and Discussion (Results and Discussion may be combined but Materials and Methods may not be combined with any other section). The Editor-in-Chief and members of the senior editorial board reserve the right to edit title, abstract, and précis for articles that are accepted to improve their clarity, brevity, and quality.

INTRODUCTION Lorem ipsum dolor sit amet, consectetur adipiscing elit. Cras egestas auctor molestie. In hac habitasse platea dictumst. Duis turpis tellus, scelerisque sit amet lectus ut, ultricies cursus enim. Integer fringilla a elit at fringilla. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nulla congue consequat consectetur. Duis ac mi ultricies, mollis ipsum nec, porta est. Mauris nec massa leo. Mauris ac diam auctor nisl imperdiet porta. Sed sit amet neque eget nisi dictum placerat. Duis sit amet pellentesque odio. Cras scelerisque sem a consectetur vehicula. Aliquam interdum luctus fringilla. Nunc sollicitudin, lorem in semper viverra, dui nisi sodales sem, ut condimentum erat leo eget arcu. Donec pharetra aliquam metus, non pulvinar tellus interdum a. Mauris a ante pharetra, mollis enim in, eleifend erat. Pellentesque suscipit risus massa, non vestibulum libero euismod feugiat. In hac habitasse platea dictumst. Maecenas rutrum lobortis lobortis. Vestibulum convallis porttitor sem ac ultricies. Mauris volutpat fringilla nisl blandit semper. Proin nec iaculis sem. Aenean neque ipsum, pretium a faucibus non, tincidunt ut sapien. Nunc a aliquet sem, eget aliquet purus. Vestibulum ac placerat mauris. Proin sed dolor ac justo semper iaculis. Donec varius, nibh sit amet finibus tristique, sapien ante interdum odio, et pretium sapien libero nec massa. In hac habitasse platea dictumst. Donec vel augue ac sapien imperdiet pretium. Maecenas gravida risus id ultricies dignissim. Maecenas gravida felis quis dolor faucibus, sed maximus lorem tristique. Nam hendrerit quam quis ante porta posuere. Fusce finibus maximus orci at porttitor. Nulla tempor ex a porttitor consequat. Quisque quis tempor eros. Donec nisi mauris, sollicitudin in dapibus eu, interdum ultricies quam. Pellentesque tincidunt lobortis orci non venenatis. Cras in justo luctus, pulvinar augue id, suscipit diam. Morbi aliquet fringilla nibh, vel pellentesque dui venenatis eget. Orci varius natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Donec ultricies ultrices magna gravida porta. Maecenas accumsan diam dui, auctor ornare ex pellentesque id. Integer tempus massa id augue finibus convallis. Nulla vestibulum, nisl id tempor pulvinar, felis dui pellentesque lacus, quis bibendum metus enim sed ex. Duis magna nunc, rutrum sodales elementum a, egestas eget dolor. Vivamus non pretium nunc, at vestibulum arcu. Vivamus pharetra, justo vel blandit feugiat, magna neque feugiat mi, a bibendum erat arcu a est. Sed vestibulum, leo non elementum condimentum, dui ipsum vehicula quam, a vehicula turpis ipsum a nibh. Mauris posuere lobortis porta. Aenean augue neque, varius vitae dapibus ac, dictum ut nisl.