Public IssuesBrief articles on topics of interest to cancer researchers and the general public. These topics might include articles on advocacy for funding cancer research, government relations, training in the field, public education, or science education.2,000 words of textAbstractThe abstract must be concise, yet should accurately outline the content of the manuscript (see the Categories of Articles page of each journal for abstract length requirements for each type of article). Because these abstracts are used by secondary services (e.g., MEDLINE, Chemical Abstracts, Web of Science, Scopus), they should recapitulate in abbreviated form the purpose of the study and the experimental technique, results, and data interpretations. Data such as the number of test subjects and controls, strains of animals or viruses, drug dosages and routes of administration, tumor yields and latent periods, length of observation period, and magnitude of activity should be included. Vague, general statements such as "The significance of the results is discussed" or "Some physical properties were studied" should be avoided. Important terms relevant to the content of the manuscript should be incorporated into the abstract to assist indexers and searchers. Abbreviations should be kept to an absolute minimum; however, if they are needed, they must be explained at first mention within the abstract so that it can be understood as an independent unit from the remainder of the manuscript. Do not cite references in the abstract.IntroductionThe introduction should provide a brief overview of the background and rationale for the study. It is not necessary to cite all of the background literature in the introduction. Brief reference to the most pertinent articles generally suffices to acquaint the reader with the findings of others in the field and with the problem or question that the investigation addresses. Sample citation \cite{Andor_2017}.Materials and MethodsExplanation of the experimental methods should be adequate for repetition by qualified investigators. Procedures that have been described in previous publications should not be described in detail but merely cited with appropriate references along with any modifications of the procedure. Only new and substantial modifications of previously published procedures need complete exposition. The sources of special chemicals or preparations used should be provided. Any commercial products that are mentioned should include the name of the manufacturer and catalog numbers.ResultsInclude a concise summary of the data presented in all display items (figures and tables). Excessive elaboration of data shown in display items should be avoided.DiscussionThe data should be interpreted concisely without repeating material already presented in the Results section. Speculation is permissible, but it must be well founded, and discussion of the wider implications of the findings is encouraged.AcknowledgmentsInclude the names of others contributing to the work who are not identified as authors.