Open burning of sugarcane residue emits a significant amount of fine particulate matter (PM) which is one of the major sources of air pollution in India. Measurement was carried out in an agricultural field of Mandya District in Karnataka, during the field preparation of Kharif crop in July 2021. PM emission from the burning of sugarcane residue was measured using the GRIMM instrument. The measurement of maximum PM1, PM2.5 and PM10 concentration during the burning was found as 432 ± 97 µg/m3,  498 ± 114 µg/m3, and 593 ± 134 µg/m3 respectively. These values were much higher than the standard PM2.5 and PM10 values specified by the regulatory agency in India. Further, the California Puff (CALPUFF) dispersion model was used to predict PM2.5 concentration using WRF (Weather Research and Forecasting) processed meteorological data and the source emission rate (ER) of 0.005 g/m2.sec. The model was simulated from 15th July 2021 to 21st July 2021 (6 days). Results showed that the maximum PM2.5 concentration predicted by the model was 942.6 µg/m3 at a distance of 464 m from the source and at a height of 10 m above the ground. Prediction from the Multiple-Path Particle Dosimetry (MPPD) Model showed the deposition dosages of PM1, PM2.5, and PM10 in the human lungs as 2.10 µg, 3.12 µg, and 5.96 µg respectively for males and 1.16 µg, 1.94 µg, and 3.68 µg respectively for female.