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<article xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="1.1" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id>authorea</journal-id>
      <publisher>
        <publisher-name>Authorea</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.15200/winn.146527.75654</article-id>
      <title-group>
        <article-title>Gene-Editing&amp;#x2014;Is the Quest to Alter a Patient&amp;#x2019;s Genome Ethical?</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name>
            <surname>Yu</surname>
            <given-names>Megan</given-names>
          </name>
          <address>
            <institution>University of Virginia</institution>
          </address>
        </contrib>
      </contrib-group>
      <pub-date date-type="preprint" publication-format="electronic">
        <day>17</day>
        <month>4</month>
        <year>2023</year>
      </pub-date>
      <self-uri xlink:href="https://doi.org/10.15200/winn.146527.75654">This preprint is available at https://doi.org/10.15200/winn.146527.75654</self-uri>
      <abstract abstract-type="abstract">
        <p>Gene-editing—the ability to alter a patient’s genome—aims to repair
deleterious genes in order to improve patient outcomes. Recent
biomedical and social science research, however, has exposed many
biological and ethical hurdles that compromise its merits. While
gene-editing holds promise to treat many detrimental diseases, it should
be approached with caution as it could have unforeseen consequences that
should be investigated with further research.</p>
      </abstract>
    </article-meta>
  </front>
</article>
