Euphorbia paraikalli, a new succulent species allied to Euphorbia susan-holmesiae Binojk. & Gopalan is described in the present communication. The species differs in its habit, wider and short segments, densely packed whorls of branches, up to 6 wings, larger leaves, trapezoidal glands, capsules with rounded lobes, and brown speckled seeds. E. susan-holmesiae is known only from a single locality in Tirunelveli District, whereas E. paraikalli is found in sporadic populations in the hills that mark the southern boundary of the Deccan Plateau.