Introduction: A decline in fertility rates is observed in Colombia and globally, with contraceptive use significantly contributing to this trend. Daily Defined Doses (DDD) of contraceptives per 1,000 females aged 15 to 49 (DID) provide insights into strategies for reducing unwanted pregnancies. This study aims to identify patterns of contraceptive use in Colombia by type and develop explanatory hypotheses regarding changes over time. Methods: Data on the female population of childbearing age (15 to 49 years) from the Unique Database of Affiliates (BDUA) and units sold of contraceptives from the Drug Price Information System (SISMED) were extracted and integrated by date. The units per commercial presentation and type of contraceptive were manually verified using health records from INVIMA, allowing for the assignment of DID for each contraceptive and analysis of trends over time. Results: The DID reveals a significant increase from 101 in 2020 to 128 in 2022, followed by a return to almost previous levels (102) in 2023. The share of combined oral contraceptives (COC) progressively increased, replacing monthly injections and Depot Medroxyprogesterone Acetate by 2023. A month-by-month analysis shows a trend toward increased use of high-dose levonorgestrel-releasing intrauterine devices and subcutaneous implants, alongside reduced use of oral contraceptives and Depot Medroxyprogesterone Acetate. Conclusions: These trends reflect a shift in contraceptive preferences among practitioners and women of reproductive age. Future research should continue to monitor these patterns and assess the implications for public health policies related to reproductive health and family planning in Colombia.